【摘要】 广东省南澳县是我国南方食管癌高发区。环境中可疑病因——亚硝胺及其前体物正日益受到人们的关注。为此，我们从当地居民所吃膳食中采集５５份样品，用ＧＣ－ＴＥＡ测定挥发性亚硝胺及其前体物。样品中检出二甲基亚硝胺（ＮＤ－ＭＡ）、二乙基亚硝胺（ＮＤＥＡ）、亚硝基吡咯烷（ＮＰＹＲ）、亚硝基哌啶（ＮＰＩＰ）及甲基苄基亚硝胺（ＮＭＢｚＡ）。它们的平均水平（中位数）为３１２．０μｇ／ｋｇ，人均日摄入总量为２８６．５μｇ。通过逐步回归及曲线拟合法研究亚硝胺、前体物及主要食物类型间的相关关系。结果表明：该地区膳食中挥发性亚硝胺含量较高。更多还原

【Abstract】 Nan’ao County in Guangdong Province was an esophageal cancer high risk area in the southern China. Of the suspected etiological factors in the environment, N nitrosamines and their precursors have been received the most attention. 55 samples of the diets ingested by the inhabitants were collected and tested for volatile N nitroso compounds and for their precursors by GC TEA. Five kinds of N nitrosamines (NDMA, NDEA, NPYR, NPIP and NMB zA) were detected in the samples. The average level of them was 312.0 μg/kg(median). The day intake of the nitrosamines was 286.5μg/head/day. By the computerized stepwise regression analysis and curve fitting, we studied the correlation among the nitrosamines, the precursors and the major food items. It demonstrated that a relatively high content of volatile N nitrosamines was present in the diets collected in the area.更多还原