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儿童胃幽门螺杆菌感染与上胃肠道疾病

Helicobacter pylori infection in the stomach and upper gastrointestinal diseases in children.

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【作者】 李瑜元胡品津潘瑞芳岳燕萍

【Author】 Li Yuyuan, Hu Pinjin,△ Pan Ruifang Yue YanpingFirst Municipal Peoples Hospital of Guangzhou (510180)△ First Affiliated Hospital, Sun Yatsen University of Medical Science. childrens Hospital of

【机构】 广州市第一人民医院

【摘要】 目的:研究儿童胃幽门螺杆菌(HP)感染的特点,以及与上胃肠病的关系。方法:对153例因胃肠症状接受胃镜检查的有连续症状的患儿进行前瞻性、活检组织学、血清学、尿素酶法检查、并与265例成年患者及181例无症状健康儿童对照。结果:患儿HP感染率29%,低于成年患者71%(P<005),与健康儿童(34%)无差异(P>005)。儿童消化性溃疡HP感染68%,高于非溃疡组22%(P<005),但显著低于成人组98%(P<005)。HP相关胃炎儿童内镜无特征、组织学炎症细胞浸润活动明显。结论:儿童HP感染是溃疡致病因素,但非唯一因素,HP感染和症状无关,HP相关胃炎有一定组织学特点。

【Abstract】 ims: To investigate the characteristics of Helicobacter pylori (Hp) infection in children and its relationship to upper gastrointestinal diseases. Methods: To study prospectively 153 consecutive symptomatic children undergoing gastroscopy by histology, serology, urease testing for Hp infection. The data of 265 symptomatic adults and 181 healthy children were used as control. Results: The rate of Hp infection in study group (29%) was lower significantly than that (71%) of adults (P<0.05), but no different from that (34%) of healthy children (P>0.05). The rate of Hp infection in peptic ulcer disease (68%) was significantly higher than that (22%) of nonulcer dyspepsia (P<0.05), but lower than that (98%) of adults (P<0.05). No endoscopic characteristics were found in Hp associated gastritis. Histologically inflammative cell infiltration and activity was obvious. Conclusions: Hp infection is an important, but not only, factor in the pathogensis of peptic ulcer in children. There is no relation between Hp infcetion and symptoms. Hp associated gastritis has same histological characteristics.

  • 【文献出处】 胃肠病学和肝病学杂志 ,CHINESE JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY , 编辑部邮箱 ,1997年02期
  • 【分类号】R573.1
  • 【被引频次】1
  • 【下载频次】34
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