【摘要】 采用穴状配体氨基聚醚２．２．２催化下的亲核取代反应，以［１９Ｆ］Ｆ－（ＫＦ）代替１８ＦＤＧ合成中的［１８Ｆ］Ｆ－与前体化合物１，３，４，６－四氧乙酰基－２－氧三氟甲烷磺酰基－β－右旋吡喃甘露糖反应，应用１８ＦＤＧ自动合成系统制备１９ＦＤＧ，并用１９Ｆ－ＮＭＲ方法验证了无载体１８ＦＤＧ合成的异构体选择性更多还原

【Abstract】 Using the 18 FDG auto synthesizing system and cryptand kryptofix 2.2.2 supported nucleophilic substitution, 19 FDG is prepared by the reaction of 19 F -(KF),instead of [ 18 F]F - in the synthesis of 18 FDG, with precursor 1,3,4,6 tetra O acetyl 2 O trifluoromethane sulfonyl β D mannopyranose, and the epimeric selectivity of no carrier added 18 FDG synthesis is identified by 19 F NMR spectroscopy.更多还原