【摘要】 首次从药用植物美丽乌头(Aconitum pulchellum)中分离得到两个内酯型降二萜生物碱,通过波谱分析,其中1个鉴定为异叶乌头碱(heteratisine,1),另1个鉴定为二乙酰异叶乌头碱(diacetylheteratisine,2)。后者从自然界还是首次得到,其结构通过1的全乙酰化进一步得以确证。更多还原

【Abstract】 Aconitum pulchellum Hand-Mazz, distributing in West of China, grows at an altitute about 3500-4500 m. Its roots have effects of activiting blood circulation and are employed to the treatment of rheumatic arthritis and some injuries. For the first time,two lactone-type norditerpenoid alkaloids, heteratisine(1) and diacetylheteratisine(2) ,were isolated and identified from the whole plants by spectral evidence and chemical transformation. Diacetylheteratisine was not report as natural product before.更多还原