【摘要】 应用视觉诱发电位(VEP)检测了113例冠心病患者和54例健康对照者。结果显示,冠心病患者VEP明显异常,异常率达30.1％。男性冠心病组VEP各波潜伏期均比对照组明显延迟,VEP异常率为39.3％;女性冠心病组VEP各波潜伏期亦较对照组明显延迟,异常率为21.1％,男、女冠心病组比较VEP异常率有显著差异。提示冠心病患者存在亚临床中枢神经损害,其视觉传导通路及视相关皮质功能明显损害,男性冠心病人较女性为重,VEP是早期诊断该病的敏感手段。更多还原

【Abstract】 Visual evoked potentials(VEP)were recorded for 113 patients with coronary heart disease(CHD) and 54 controls to elucidate the involvement in the visual pathway and vision-related cortex. The results showed that the latencies of all peaks in man and woman patients with CHD were prolonged significantly, compared with the man and woman controls respectively; and abnormal VEP were demonstrated in 39. 3% of man patients and 21. 1 % of woman patients(30. 1% of all patients) ,and the latencies of peaks and VEP abnormalities in man patients group were increased significantly as compared to the woman patients group. These results confirmed that the subclinical CNS involvement was presented in patients with CHD(i. e. visual pathway and vision-related cortex dysfunction). The male patients had more changes to get subclinical CNS involvement than the female. The VEP analysis can be used as a sensitive tool to diagnose CHD initially.更多还原