【摘要】 采用固定角转头15000r/min、8℃高速离心,将红细胞按胞龄分为少龄、中龄和老龄,分别聚集在离心管上、中、下三层。结果表明,随着红细胞在外周血中走向衰老,其胰岛素结合能力和ATP、NAD浓度都显著降低。这种变化有3种可能解释:1.成熟红细胞不再有蛋白质合成能力。2.与红细胞整个发育过程中,不断走向适应于担负简单而又特殊的生理功能的趋势有关。3.这种变化很大程度上是人体各种细胞衰老过程机制所决定的。更多还原

【Abstract】 Centrifugated at 15,000rpm,8℃,for 60 minutes,the red blood cells were divided Into younger, mid-age and older RBC respectively referred to upper, medial and lower layers. After several experiments introduced below.it was found that the insulin binding capability and ATP,NAD declined when the cells became older. It was suggested that the reasons may be:1. deprivement of protein production; 2. extend of erythrocytes to simple physiological function;3. mechanism of human cellular aging procedures.更多还原