【摘要】 本研究观察了补肾益精方药固真方对老年大鼠胸腺重/体重比值,老年大鼠胸腺细胞三碘甲状腺原氨酸（T₃）受体数、Na⁺-K⁺-ATP酶活性以及下丘脑、血浆亮氨酸脑啡肽（L-EK）含量的影响。结果表明:老年大鼠胸腺重/体重比值,胸腺细胞T₃受体数、Na⁺-K⁺-ATP酶活性以及血浆亮氨酸脑啡肽（L-EK）含量均明显低于青年对照鼠,下丘脑L-EK含量则显著高于青年对照鼠,而固真方能明显改善老年大鼠胸腺三碘甲状腺原氨酸（T₃）受体、Na⁺-K⁺-ATP酶活性的改变,提示固真方可能通过增加老年大鼠降低的胸腺细胞T₃受体数和提高胸腺摄取T₃的功能,从而增强甲状腺激素（T₃）对胸腺的促进作用,提高老年机体胸腺依赖性免疫功能。更多还原

【Abstract】 The effects of Guzhen Recipe (GZ), a tonifying kidney essence prescription which is composed of Ploygonum multiforum, Cistanche deserticole etc, on the thymic (Na+,K+)ATPase Activity, the number of 3, 5, 5’-triiodothyronine receptor (T3R) sites in thymocyte and the leu-enkephaline(L-EK) content in hypothalamus and plasma were observed.The results showed compared with that of young control group, the thymic (Na+ ,K+) ATPase Activity, the number of T3R sites in the thymocyte and the L-EK content in plasma of senile rat were significantly decreased, while L-EK content in hypothalamus was increased obviously. GZ, however, was capable of improving the number of T3R and (Na+,K+)ATPase activity in senile rat markedly suggesting that GZ might enhance the thymus-dependent immune function on senile rats by means of increasing the lowered number of T3R sites in thymocyte as well as Aie T3 uptake function on thymus.更多还原