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习惯性流产患者丈夫精子核染色质状态评价
The Evaluation of the Sperm Chromatin Status from Spouses of Women with Spontaneous Abortion
【摘要】 对31例习惯性流产患者丈夫精液和35例具正常生育能力非习惯性流产者丈夫的精液进行质量检查分析,并对31例习惯性流产中的21例精液标本,进行了精子核吖啶橙诱发荣光检查.结果显示,两组间精液液化时间、pH值、精子密度、精子成活率、运动能力无明显差异;两组间异常精子百分率有明显差异(P<0.01);两组间发黄色荧光、红色荧光精子百分率有显著差异(P<0.01)。结果提示,胚胎早期丢失的原因可能与精子核染色质异质性密切相关。
【Abstract】 Semen samples from husbands of women with habitual abortion (n= 31) and from normal fertile donors (n= 35) were subjected to conventional semen analysis, and acridine orange nuorescence was performed on 21 of 31 cases, no significant difference was detected between liquefaction time (min), pH, the sperm concentration (×109/L), sperm vital ratio (% ), and motility (%). However, the difference in abnormal sperm morphology of the two groups was significant (P<0.01), and tbe difference in percentage of yellow fluorescence sperms and red fluorescence sperms was markedly significant (P<0.01). The results suggest that the presence of the sperm chromatin heterogenity may lead to a result of early pregnancy loss.
【Key words】 acridine orange test; abortion, habitual; sperm atozoa; chromatin;
- 【文献出处】 同济医科大学学报 ,ACTA UNIVERSITATIS MEDICTNAE TANGJI , 编辑部邮箱 ,1997年01期
- 【分类号】R714.2
- 【被引频次】3
- 【下载频次】56