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经皮穿刺输精管吸精子宫腔内授精治疗阻塞性无精症不育

Percutaneous vasal sperm aspiration and intrauterine insemination in the treatment of obstructive azoospermia

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【作者】 邱毅王苏梅樊云井杨丹彤苏启昌鲁华王志新田奎武黄真嘉

【Author】 QIU Yi, WANG Sumei, FAN Yunjing,YANG Dantong,SU Qichang, LU Hua, WANG Zhixin, Tian Kuiwu, HUANG ZhengjiaShandong Institute of Family Planning, Jinan 250002

【机构】 山东省计划生育科学研究所

【摘要】 对276例无精症不育患者采用睾丸细针穿刺吸液细胞学检查,结合精液生化指标测定及双侧输精管通液或造影技术,6例诊断为双侧输精管盆部阻塞性无精症,经皮穿刺输精管吸精子(PVSA),有4例吸出活精子,2例吸出死精子,经孵育活化后,精子活率0%~48%,畸形精子31%~82%,吸出液内总精子数(2~60)×106,对3例吸出活精子患者行宫腔内人工授精(IUI)4个月经周期,结果1例妊娠,并足月剖宫产一健康女婴,体重2650g,身长47cm。提示经皮穿刺输精管吸精子IUI,可以做为输精管盆部阻塞性无精症不育患者一种有效的治疗方法。

【Abstract】 Objective: To treat obstructive azoospermia by using percutaneous vasal sperm aspiration(PVSA) and intrauterine insemination(IUI).Setting: Shandong Institute of Family Planning.Design: Clinical study.Methods: Six men with obstructive azoospermia,three were treated with IUI,the spermatozoa used for IUI were retrieved by PVSA,and incubated at 37℃ for 40~60 min.Results: Intrauterine insemination was carried out in three patients for 1 ̄2 cycles,with motile spermatozoa.One successful term delivery was obtained.Conclusion: Percutaneous vasal sperm aspiration can be used successfully to recover sperm in men with obstructive azoospermia for use in IUI.The technique is simple and less traumatic as compared with an open surgical procedure.

  • 【文献出处】 生殖医学杂志 ,JOURNAL OF REPRODUCTIVE MEDICINE , 编辑部邮箱 ,1997年04期
  • 【分类号】R698.2
  • 【被引频次】10
  • 【下载频次】44
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