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胃癌患者胃液可溶性白细胞介素-2受体初步研究

Preliminary Studies on Gastric Juice sIL-2R Levels in Patients with Gastric Cancer

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【作者】 张博芬; 刘义新; 朱晓敏; 申丰; 张力达; 赵旭萍; 宋俊焕;

【Author】 Zhang Bo fen, Liu Wenxin,Zhu Xiaomin,et al. (Department of Mitrobiology)

【机构】 沈阳医学院医学基础部微生物学教研室; 沈阳医学院附属二院内镜室; 辽宁省科技情报所;

【摘要】 应用双抗体夹心ELISA法对87例消化道疾病患者胃液可溶性白细胞介素-2受体(sIL-2R)水平进行测定。结果表明,胃癌患者胃液sIL-2R水平明显高于慢性浅表性胃炎及十二指肠溃疡患者(P<O.01);男性胃癌患者sIL-2R水平显著高于女性胃癌患者(P<0.05);60~79岁胃癌患者胃液sIL-2R水平高于40~59岁患者(P<0.05);贲门癌sIL-2R水平高于胃窦癌水平。结果提示,胃液sIL-2R的测定对胃癌患者判断病情和估计预后具有重要意义。

【Abstract】 87 patients with gastric disease were detected for gastric juice sIL-2R levels by using a sandwich ELISA. The results showed that the mean level of gastric juice sIL-2R in gastric cancer was much higher than those of chronic gastritis and gastro-duoden ulcer ( P <0. 05) (Gastric juice sIL-2R level in male patients with gastric cancer was higher than that of female patients ( P <0. 05). The gastric juice sIL-2R level in 60-79 year-old-patient with gastric cancer was higher than that in 40-59 year-old-patient ( P <0. 05)籹IL-2R level was also connected with the location of gastric cancer. It can be prompted that detecting the gastric juice sIL-2R level has great significance to assess the patients condition and estimate the prognosis in gastric cancer.

【关键词】 可溶性白细胞介素2受体; 胃癌;
【Key words】 sIL-2Ri gastric cancer;
  • 【文献出处】 沈阳医学院学报 ,Journal of Shenyang Medical College , 编辑部邮箱 ,1997年03期
  • 【分类号】R735.2
  • 【下载频次】12
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