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云芝糖肽对受照小鼠骨髓移植的影响
The Effects of Ps-P on Bone Marrow Transplantation in the Mice Exposed to Irradiation
【摘要】 BALB/C小鼠经60Coγ射线致死剂量照射后移植同系骨髓细胞,观察腹腔注射云芝糖肽对造血重建的影响。结果表明,云芝糖肽骨髓移植前用药组存活率、存活时间及脾集落形成单位,较单纯骨髓移植对照组明显提高,且能减轻外用血白细胞的降低,促使白细胞恢复。
【Abstract】 By Using BALB/C mice exposed to lethal dose of 36Coγ-rays, transplantation of homologous bone marrow was made.The ef feets of the intraperitoneal administration of Ps-P on hematopoietic reconstruct was observed. The results showed that: Survive ra tio, survie time and CFU-S were markedly higher in the group of Ps-P administration before BMI than that in the BMI control group(<0.01) and in Ps-P peripheric blood leukocytopenia could be alleviated and leukocyte recovering could be improved.
【关键词】 云芝糖肽;
60Coγ射线;
骨髓移植;
脾集落形成单位;
【Key words】 Polysaccharide-Peptide(Ps-P); 60Coγ-rays; Bone marrow transplantation(BMT); Spleen colony forming units(CFU-S);
【Key words】 Polysaccharide-Peptide(Ps-P); 60Coγ-rays; Bone marrow transplantation(BMT); Spleen colony forming units(CFU-S);
- 【文献出处】 苏州医学院学报 ,ACTA ACADEMIAE MEDICINAE SUZHOU , 编辑部邮箱 ,1997年05期
- 【分类号】R285
- 【被引频次】2
- 【下载频次】49