【摘要】 以唐山市郊区及县区新诊断的１０１例乳腺癌患者为对象，按性别、年龄、出生地、生活地等因素与相同数量的对照者进行１∶１配比的病例对照研究。在单因素分析中，筛选出绝经年龄迟、行经期长、初产年龄晚、体重大、良性乳腺疾病史及精神刺激为乳腺癌的危险因素。生育次数、总哺乳期、初潮年龄、初潮～初产间隔、初产～末产间隔、口服避孕药、吸烟、饮酒、文化程度、乳腺癌家族史等指标，未发现与乳腺癌有明显联系。将上述因素引入条件Ｌｏｇｉｓｔｉｃ回归模型进行多因素分析，结果与单因素分析一致。更多还原

【Abstract】 A hospitalbased matching casecontrol study was conducted in Tangshan rural area. In this study 101 cases with new diagnosed breast cancer and the same number controls matched on sex, age, and the area of birth and live were investigated in hospitals. Late age at menopause, long menstrual periods, late age at first birth, heavy weight, history of benign breast disease and mental stress were found to increase risk, which was confirmed by the findings from multivariate analysis using conditional Logistic regression model. No obvious relationship was found between breast cancer and indexes such as parity,lactation, age of menarche, the interval between menarche and the first birth and between the first birth and the last brith. Other factors such as oral contraceptive use, smoking, drinking, educational level and family history of breast cancer were also not found to be related to the risk. There was no difference between the result of single factor analysis and that of multiple factor analysis.更多还原