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甲状腺癌GST-π基因表达的研究
The Expression of GST π mRNA in Thyroid Carcinoma
【摘要】 应用逆转录PCR技术,检测甲状腺癌及癌旁组织GSTπ基因表达。结果表明:10例甲状腺癌有4例GSTπ基因表达阳性,而10例癌旁组织GSTπ基因表达阴性。提示:GSTπ基因表达与甲状腺细胞恶性转化有关。
【Abstract】 The expression of GST π gene in thyroid carcinoma and the tissues adjacent to carcinoma was analyzed by reverse transcription polymerase chain reaction (RT PCR) technigue. The result showed that in 4 of 10 cases of thyroid carcinomas the expression of GST π mRNA was positive, but in 10 cases of tissues adjacent to carcinoma was negative. Our result suggest that the expression of GST π mRNA is related to the malignant transformation of thyroid cell.
【基金】 国家自然科学基金
- 【文献出处】 实用癌症杂志 ,THE PRACTICAL JOURNAL OF CANCER , 编辑部邮箱 ,1997年01期
- 【分类号】R736.1
- 【被引频次】1
- 【下载频次】29