【摘要】 根据发现青少年胆囊结石病人有胆囊管解剖异常现象，设计了动物兔胆囊管不全梗阻可形成胆囊结石的假说。取健康家兔２４只，雌雄不限，体重２．５ｋｇ～３．０ｋｇ，在无菌条件下行剖腹术，随机分实验组（胆囊管不全结扎１７只）和对照组（假手术７只）。成石标准以肉眼可见颗粒状或团块状结石或褐色糊状胆泥为准，并经Ｂ超、手术和病理证实。实验组成石率为６４．７％（１１／１７），对照组为１４．３％（１／７），经χ２检验，Ｐ＜０．０２５。实验表明，兔胆囊管不全梗阻与胆囊结石形成间存在着因果关系。更多还原

【Abstract】 The abnormalities of the cystic duct in young patient with gallstones were observed by operations.We proposed a hypothesis that the incomplete stricture of the cystic duct is related to the formation of gallstone.Animal experiments were undertaken to test the hypothesis.Twenty four healthy rabbits with a weight of 2.5 to 3.0 kilograms,either male or female,were undergone laparotomies.The animals were randomly divided into experimental group(incomplete stricture of cystic duct) and control group(sham operation).There were 17 rabbits in experimental group,7 in control group.The standards for stone formation were macroscopic stone of sludge,confirmed by ultrasound,operation and pathology.The rate of stone formation was 64.7 per cent (11/17) in experimental group,14.3 per cent (1/7) in control group,with a statistically significant difference (P<0.025).The results showed that the cause and effect relationship occurs between the incomplete stricture of cystic duct and gallstone formation.confirming the proposed hypothesis.更多还原