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胆道梗阻的时间与血浆内皮素、心钠素的关系
The relation of the time of obstructive jaundice and endothelin as well as atrial natriuretic peptide
【摘要】 观察不同时间的OJ病人血浆ET、ANP含量及其与肝、肾、心、肺等多脏器功能指标的关系,结果在OJ病人血浆中ET、ANP含量增加,且与多脏器功能损害密切相关。提示ET、ANP可以作为OJ病情及其脏器功能的判断指标;ET在OJ并发症中有明显的发病作用,而ANP作为ET的拮抗物在OJ引起的多脏器功能失常综合征中可能具有保护作用。
【Abstract】 The serum contents of endothelin(ET)and atrial natriuretic peptide(ANP)in patients with oJ and their relation with the damage index of hepatic,renal cardiac and gastrointestinal function in periods of obstructive jaundice(OJ)were observedIt showed that the contents of ET and ANP increased in OJThe longer the time of OJ,the more the contents of ET and ANPThe contents of ET and ANP closely related with the multiple organs dysfunctionThis showed ET and ANP may serve as a synthesis traget of judgement of state of the illness and the damage of multiple organs functionET has an evident effect on the invasion of multiple organs dysfunction complicated with OJAs an antagonist of ET,ANP has a protective effect on the multiple organs dysfunction in OJ
【Key words】 jaundice,obstructive; endothelin; atrial natriurtic peptide; multiple organs dysfunction;
- 【文献出处】 山西医科大学学报 ,JOURNAL OF SHANXI MEDICAL UNIVERSITY , 编辑部邮箱 ,1997年04期
- 【分类号】R575
- 【下载频次】10