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平阳霉素局部注射治疗婴儿颜面部血管瘤32例

Intratumor injection of pingyangmycin for treatment of facial hemangioma in infants: report of 32 cases

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【作者】 黄河

【Author】 Huang He. The people’s hospital of Lianjiang(524400)

【机构】 广东省廉江市人民医院整形科

【摘要】 为寻求简单有效的治疗方法,采用平阳霉素局部注射治疗婴儿颜面部血管瘤。具体方法是:将平阳霉素8mg+生理盐水3~5ml+2%利多卡因0.5ml稀释待用。取平阳霉素稀释液行血管瘤内注射至肿胀苍白为度,可见用药3天内血管肿胀变黑褐色,以后逐渐变白、变平、消失。若血管瘤较大,一次用药未愈者,可每隔1~2周重复用药一次,直至治愈为止,一般总用药量不超过40mg。1992年1月~1995年12月,用该法治疗2~6个月龄婴儿颜面部血管瘤32例,其中草莓状血管瘤20例,海绵状血管瘤8例,混合型血管瘤4例。血管瘤最小面积1.0cm×1.5cm,最大面积4.0cm×5.0cm,经1次注射治愈8例,2~3次注射治愈21例,面积最大的1例经4次注射而愈。经2个月~3年的随访,总有效率达100%。认为该法具有简单,疗效显著,并发症少等优点,只要正确掌握治疗方法,可以不遗留畸形,特别适于婴儿颜面部中小面积草莓状血管瘤,海绵状血管瘤,混合型血管瘤的治疗。

【Abstract】 Hemangioma is a common congenital tumor or malformation. we use intratumor injection of Pingyangmycin to treat infant facial henamgioma. 8mg of Pingyangmycin is dissolved in 3~5ml of normal saline and 0.5ml of 2% Lidocaini, the Pingyangmycin solution is injected into hemangioma till it begins to swell and get pale. The hemangioma changes to black and brown colour in three days, and getting paler and flatter until it disappears. the drug can be used once again in one or two weeks with a total dose not more than 40mg. From January 1992 to December 1995, Pingyangmycin injection was used to treat 32 cases of facial hemangioma in infant, aged 2~6 months induding 20 cases of strawberry hemangioma, 8 cases of caverour henangioma and 4cases of mixed hemangioma. The sige of hemangioma is 1.0cm×1.5cm to 4.0cm×5.0cm. 10 cases were cured by injecting only once, 21 cases two or three times, one case with largest hemangioma in this group was cured by four times of injection , the effective rate is 100%in two months to three yesrs follow up. It is especially suitable for infant facial strawberry hemangioma,cavernous hemangioma and mixed hemangioma of small amd midlle sige.

【关键词】 平阳霉素血管瘤局部注射
【Key words】 PingyangmycinHemangiomaLocal injection
  • 【文献出处】 实用美容整形外科杂志 ,JOURNAL OF PRACTICAL AESTHETIC AND PLASTIC SURGERY , 编辑部邮箱 ,1997年03期
  • 【分类号】R543.7
  • 【被引频次】12
  • 【下载频次】57
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