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大鼠中枢神经系统衰老的形态学研究—红核神经元的超微结构改变

MORPHOLOGIC STUDIES ON AGING OF CENTRAL NERVOUS SYSTEM OF RAT-ULTRASTRUCTURAL CHANGES IN THE NEURONS OF RED NUCLEUS

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【作者】 张兵侯家骥高峻黄岩

【Author】 Zhang Bing; Hou Jiaji; Gao Jun; Huang Yan(Department of Histology and Embryology, Lanzhou Medical College;Department of Obstetrics. The 2nd Affiliated Hospital Lanzhou Medical College, Lanzhou)

【机构】 兰州医学院组织学与胚胎学教研室!兰州730000

【摘要】 本文对不同年龄组雄性SD大鼠红核神经元的超微结格进行了观察,结果表明:(1)红核神经无核周体中脂褐素在幼年组已开始出现,并随增龄增多,其附近线粒体的形态有所改变,该周体中其他细胞器随增龄也有一定程度的形态改变;(2)红核神经元细胞核随增龄出现核膜内折现象;(3)在老年级红核神经处观察到微丝缠绕线粒体群的现象.上述结果说明红核神经元随增龄确实存在着一定的形态学改变.

【Abstract】 Ultrastructurial changes in the neurons of red nucleus in rats of male Spraque-Dawley struin divided into threegroups, young, adult and senescent were studied. The results demonstrated that (1) a few lipofuscin were observed in theyoung group, and the number of lipofuscin was increased markedly with advancing age; mitochondria near the lipofuscinwere clianged; the other organelles in perikaryon were changed to an extent; (2) the nucleilr membrane invagination was ob-served markedly in the senescent group; (3) the phenomenon of mitochondria surrounding by microfilaments in dendrites inneuropile of the senescent group was observed. The results indicate that there are morphologic changes of red nucleus withadvancing age.

【关键词】 神经元红核衰老超微结构大鼠
【Key words】 neuronred nucleusagingultrastructurerat
  • 【文献出处】 神经解剖学杂志 ,CHINESE JOURNAL OF NEUROANATOMY , 编辑部邮箱 ,1997年04期
  • 【分类号】R329
  • 【被引频次】1
  • 【下载频次】63
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