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慢性乙肝患者外周血单个核细胞mIL-2R的检测
Determination of mIL-2R in PBMC of chronic hepatitis B patients
【摘要】 用生物素-链霉亲和素免疫细胞化学法检测慢性乙型肝炎(CH-B)患者外周血单个核细胞(PBMC)静息状态及PHA诱导后膜白介素-2受体(mIL-2R)表达水平,结果显示CH-B患者T淋巴细胞处于部分激活状态,其对PHA的应答能力未见明显低下.CH-B患者PHA诱导后mIL-2R表达水平可作为评价病情和考核疗效的指标之一。
【Abstract】 The mIL-2R+ cells in PBMC of 159 CH-B patients were detected by immunocytochemistry method using biotin-streptavidin reagent in silent and PHA-induced phase. The result shows that T lymphocytes of CH-B patients are partly in activated state, but the response to PHA of their PBMC is normal. The percentage of mIL-2R+ cells of CH-B patients is regarded as one of the indications of assessing CH-B patients condition and the therapeutic effect.
- 【文献出处】 上海医学检验杂志 ,SHANGHAI JOURNAL OF MEDICAL LABORATORY SCIENCES , 编辑部邮箱 ,1997年01期
- 【分类号】R512.6
- 【被引频次】2
- 【下载频次】12