【摘要】 为研究耳鼻咽喉科恶性肿瘤患者与正常人红细胞免疫功能的差异，观察手术治疗前后肿瘤患者红细胞免疫功能的变化，用红细胞Ｃ３ｂ受体花环率（ＲＣＲ）、红细胞免疫复合物花环率（ＲＩＣＲ）、肿瘤红细胞花环率（ＴＲＲ）作为观察指标，测定了正常人３０例和耳鼻咽喉科恶性肿瘤４０例的红细胞免疫功能。结果表明，肿瘤患者的ＲＣＲ、ＴＲＲ明显低于正常人（Ｐ＜０．０１），而ＲＩＣＲ明显高于正常人（Ｐ＜０．０１），ＲＣＲ与ＲＩＣＲ呈负相关，提示肿瘤患者红细胞免疫功能低下是继发性的。各类肿瘤患者上述指标无明显差异，提示红细胞免疫粘附活性下降是耳鼻咽喉科恶性肿瘤的共同特征。术后ＲＣＲ、ＴＲＲ升高，ＲＩＣＲ明显下降（Ｐ＜０．０１），但与正常人比较仍有差异，提示宿主免疫与肿瘤之间的作用和影响是相互的。更多还原

【Abstract】 Adherence of erythrocytes to antigen-antibody-complement complexes (red cell immune adherence, RCIA ) may represent a basic immune phenomenon. In this study, erythrocyte immune adherence function were detected in 40 patients with otorhinolaryngeal malignant tumour using simple morphologic methods. The rate of RBC-C3b receptor rosettes (RCR) and tumour-RBC rosettes (TRR) in patients was much lower than that of normals (p<0. 01 ). But ,the rate of red blood cell immune complex rosettes (RICR)was higher(P< 0. 01 ) . RCR and TRR were significantly elevated on 14th day after removal of the tumour (p < 0. 01 ) . RICR was significantly lowered. While , compared with normals , the immune function of the operated patients was still depressed in some degree.更多还原