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蓝斑核内微量注射吗啡对颏舌肌功能的影响

THE EFFECTS OF MORPHINE INJECTED INTO LOCUS COERULEUS ON THE GENIOGLOSSAL MUSCLE ACTIVITIES

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【作者】 王凤斌刘磊

【Author】 Wang Fengbin Liu Lei (Dept.of Physiology,Shandong Medical University)

【机构】 山东医科大学生理学教研室

【摘要】 向23只健康家兔的蓝斑核(LC)内微量注射吗啡,观察对颏舌肌功能的影响。结果表明,注入微量吗啡后颏舌肌肌电积分幅度降低,频率减慢,而且此效应可被钠洛酮阻断,提示LC内存在吗啡受体,对颏舌肌的活动有抑制效应。

【Abstract】 The integrated electromyographic activities of genioglossal muscles were recorded on 23 adult rabbits to study the effects of morhpine injected into locus coeruleus (LC).The results indicated that activities of genioglossal muscles were decreased and these effects could be reversed by naloxone microinjected into the same area.This suggest that opiate receptors exist in the LC and inhibitory effects on activities of genioglossal muscles.

【关键词】 蓝斑核颏舌肌吗啡钠洛酮
【Key words】 Locus coeruleusGenioglossal muscleMorphineNaloxoneRabbits
  • 【文献出处】 山东医科大学学报 ,ACTA ACADEMIAE MEDICINAE SHANDONG , 编辑部邮箱 ,1997年01期
  • 【分类号】R-33
  • 【被引频次】1
  • 【下载频次】28
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