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应用 PCR 方法检测大肠癌组织中的 HPV DNA
Detection of Human Papillomavirus(HPV) DNA in the Tissue of Colon Carcinoma with PCR
【摘要】 本文采用聚合酶链式反应(PCR)的方法,对20例大肠癌患者的手术切除标本进行了人体乳头瘤病毒(HPV)DNA的检测。结果发现4例(20%)HPV16型扩增阳性,其中1例显示HPV16.18型双重阳性。初步表明大肠癌组织中存在HPV的感染。
【Abstract】 The detection of HPV DNA was done on surgical specimens of 20 patients with colon carcinoma with polymerase chain reaction(PCR)technic.Four of the 20 samples were positive for HPV 16 DNA including one positive both for HPV 16 and 18. The results indicated the probable association of HPV infection with colon carcinoma development.
【关键词】 大肠癌;
人体乳头瘤病毒;
聚合酶链式反应;
【Key words】 Colon carcinoma Human papillomavirus Polymerase chain reaction(PCR);
【Key words】 Colon carcinoma Human papillomavirus Polymerase chain reaction(PCR);
- 【文献出处】 齐鲁肿瘤杂志 , 编辑部邮箱 ,1997年02期
- 【分类号】Q78
- 【下载频次】35