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氟磺胺草醚的毒性研究
Study on the Toxicity of Fomesafen
【摘要】 氟磺胺草醚大鼠经口LD50为3160毫克/公斤(雄),2870毫克/公斤(雌);小鼠经口LD50为4220毫克/公斤(雄),4300毫克/公斤(雌);大鼠经皮LD50>4640毫克/公斤,对家兔眼粘膜、皮肤无明显刺激作用。Ames小鼠骨髓细胞微核试验和小鼠精子畸形试验均为阴性,无致突变作用。
【Abstract】 The general and genetic toxicity of fomesafen was studied.Its LD 50 was 3160mg/kg for male rats,2870mg/kg for female rats and 4220~4300mg/kg for mice by oral administration.Its LD 50 was more than 4640mg/kg for rats by dermal administration .There was no obvious irritative to eyes and skin of rabbits.The result of Ames test,micronucleus test and sperm malformation test was negative and no mutagenicity.
- 【文献出处】 农药 ,PESTICIDES , 编辑部邮箱 ,1997年07期
- 【分类号】TQ1450.2
- 【被引频次】11
- 【下载频次】213