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人巨细胞病毒活动性感染的研究

Study of active human cytomegalovirus (HCMV) infection

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【作者】 姜凌云周丛乐刘景城王颖黄建萍冯琪刘纪川那晓元戚豫

【Author】 Jiang Lingyung,Zhou Congle,Liu Jingchen,et al (Pediatrics of Ist Teaching Hosp.,Beijing Med.University)

【机构】 北京医科大学第一医院儿科

【摘要】 报道162例小儿活动性人巨细胞病毒感染的临床研究。所有病例CMV-IgM抗体皆阳性。48/71例尿中找到巨细胞包涵体。先天性感染组79例,其中全身性感染32例。年龄3周~12周组29例。该两组临床表现以病理性黄疸、肝脾肿大和肝损害为主,余为先天畸形和神经系统异常(17/31例有听通路传导障碍)。先天组中新生儿窒息20例。>12周龄组54例,其中肾病、肾炎或不明原因的血尿、蛋白尿共32例。死亡4例。借此以加深对该病的认识

【Abstract】 cases of childhood active HCMV infection were reported and their clinical features were studied.HCMV-IgM antibody were positive in all cases.Cytomegalic inclusion were found in the urine of 48/71 cases.Among the 79 cases of congenital infection group,32 cases were general infection.Twenty-nine cases were from 3 weeks to 12 weeks old.The clinical features in the above 2 groups were mainly manifested by pathological jaundice,hepatosplenomegaly and abnormal liver function.others had congenital malformations and nervous syetem abnormality (Auditory Brainstem Response in 17/31 cases were abnormal).There were 20 asphyxial newborns in the congenital group Among the 54 cases over the age of 12 weeks,there were 32 cases of nephropathy,nephritis or blood urine,Proteinuria of unknown causes,Four cases were dead.This Paper intended to make HCMV infection more impressive.

【关键词】 人巨细胞病毒感染
【Key words】 Cytomegalovirus,humanInfection
  • 【文献出处】 宁夏医学杂志 ,NINGXIA MEDICAL JOURNAL , 编辑部邮箱 ,1997年03期
  • 【分类号】R373.11-3
  • 【被引频次】2
  • 【下载频次】40
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