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实验性膜性肾炎的中药疗效对比研究

A CONTRAST STUDY OF THERAPEUTIC EFFECT OF HERB MEDICINE IN EXPERIMENTAL MEMBRANOUS GLOMERULONEPHRITIS

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【作者】 周青波夏养志王广钧杨海萍王鹏宇王静全章维王志永

【Author】 Zhou Qingbo Xia Yangzhi Wang Guangjun Yang HaipingWang Pengyu1 Wang Jing1 Quan Zhangwei1, Wang Zhiyong(Department of pathology, 1. Inner Mongolia Sino-Mongolia Medical Institute )

【机构】 内蒙古中蒙医研究所

【摘要】 选用中医经验方剂马钱子散用于家兔实验性膜性肾炎的治疗,同时选用中医临床治疗该病常用药物昆明山海棠和雷公藤作对比研究,结果显示马钱子散对膜性肾炎的疗效明显优于昆明山海棠,与雷公藤相近,表现在减少尿蛋白,清除免疫复合物方面尤为显著,且对肝脏损害轻微,对肾、脊髓未见明显毒副作用。在治疗慢性肾炎方面是一种有前途的药物。

【Abstract】 Strychnos nux-vomica powder was applied in treating experimental membranous glomerulonephritis in rabbits for comparison. A contrast study with Tripterygium hypoglaucum Hutch and Tripterygium wilfordii Hook which were commonly used in clinical medicine was carried out in rabbits in a similar manner. Results showed that the therapeutic effect of Strychnos nux-vomica powder was distinctly superior to Tripterygium hypoglaucum Hutch and similar to Tripterygium wilfordii Hook, as the former red reduced albuminuria, elimination of immunocomplex formation was especially striking, hepatic damage was slight, and on apparent side effect to kidney and spinal cord was observed.

  • 【文献出处】 内蒙古医学院学报 ,ACTA ACADEMIAE MEDICINAE NEIMONGOL , 编辑部邮箱 ,1997年01期
  • 【分类号】R361.1
  • 【被引频次】9
  • 【下载频次】54
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