节点文献

恶性肿瘤患者血清自然杀伤细胞抑制因子的观察

Serum natural killer cell suppressive factor in the patients with malignant tumors

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 江圣勇李新龙周俊裕王雪君

【Author】 Jiang Shengyong; Zhou Junyu; Wang Xuejun. Ningbo(Mi. 2 Hospital, et al, Ningbo 315010 )

【机构】 宁波市第二医院!315010宁波海洋学校海军412医院宁波市江东曙光医院

【摘要】 观察了20例恶性肿瘤患者血清对正常人自然杀伤细胞(NKC)活性的影响,发现荷瘤者血清可使正常人NKC活性明显抑制,其抑制率达78.9%,伴转移癌患者血清的抑制率明显高于不伴转移者。同时证实,癌症患者血清NKC抑制因子活性可被消炎痛部分阻断,而一定剂量的白细胞介素-2则无明显阻断作用,提示癌症患者血清存在的NKC抑制因子与肿瘤的发生发展密切相关,其本质可能是多因素的。

【Abstract】 The influece of serum in 80 malignant tumors cases to natural killer cell (NKC) activity of normal controls was studied.The results showed serum of tumor-bearing patients sup pressed 78. 9% of normal control NKC activity. This serum suppressive activity in the patients with matastatic tumors were apparently higher than those without - metastases. Otherwise,this suppressive activity could be partly blocked by in domethacin, hut not by smalll dose recombinant interleukin2. So it may suggest that serum NKC suppressive factor in tumor - bearing patients was closely related with developing and advancing of malignant tumors, however it’s essence might might be multifarious.

  • 【文献出处】 现代实用医学 ,Modern Practical Medicine , 编辑部邮箱 ,1997年03期
  • 【分类号】R730.43
  • 【被引频次】1
  • 【下载频次】15
节点文献中: 

本文链接的文献网络图示:

本文的引文网络