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乳腺癌DNA含量与血管浸润转移机制的研究

A STUDY ON CONTENT OF DNA OF CARCINOMA OF MAMMARY GLAND AND MECHANISM OF INFILTRATION AND METASTASIS OF BLOOD VESSEL

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【作者】 殷平; 李静; 李志强; 缪智辉; 刘林;

【Author】 Yin Ping; et al

【机构】 牡丹江医学院病理教研室!157011; 牡医学院附属医院; 牡丹江市第一医院;

【摘要】 通过流式细胞仪(FCM)测细胞DNA含量及维多利亚兰和HE复合染色法染血管,对乳腺癌病人进行浸润转移机制的研究。乳腺癌细胞中异倍体肿瘤其血管浸润的阳性率和术后复发都较二倍体肿瘤高。乳腺癌病人血管浸润的阳性率为48%,术后复发病人血管浸润阳性率为67%。直径在2.0cm以下的肿瘤,肿瘤直径与血管浸润呈正相关,超过2.0cm的肿瘤血管浸润的阳性率不再增加。淋巴结转称程度加重,血管浸润阳性年增加,n1β期以上的肿瘤可作为血管浸润的重要指标。

【Abstract】 A study on mechanism of infiltration and metastasis was conducted in patients of carcinoma of mammary gland by FCM and complexly staining the blood vessels with wttortablue and HE.Positive rate and recuring rate of vascular infiltration in tumours of DNA aneuploid were hisher than that in diploid. The positive rate of vasculer infiltration was 48 % in patients of carcinoma of mammary gland, recuring rate was 67% in those patients after operation. The diameter and vascular infiltration were direct correlation in the tumours which diaxneter was less than 2cm, positive rate of infiltration did not increase any longer in triose larger than 2. 0cm. The heavier the extent of lymphatic metastasis was, the higher the positive rate increased. The tumours after n1βstage can be regraded as the important targets of vascular infiltration.

【关键词】 乳腺癌; DNA含量; 转移;
【Key words】 Carcinoma of mammary gland; content of DNA; metastasis;
  • 【文献出处】 牡丹江医学院学报 ,JOURNAL OF MUDANJIANG MEDICAL COLLEGE , 编辑部邮箱 ,1997年01期
  • 【分类号】R737.9
  • 【下载频次】16
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