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米非司酮终止早孕375例临床疗效

CLINICAL EFFECT OF MIFEPRISTONE TABLET IN TERMINATING 375 EARLY PREGNANCY CASES

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【作者】 王默王娅沈媛谈洁

【Author】 WANG Mo WANG Ya SHEN Yuan (Wuhan Central Railway Hospital, Wuhan 430064)

【机构】 武汉铁路中心医院!武汉430064凯斯妇产科联合诊所!武汉430023

【摘要】 375例早孕妇女,分组用po米非司酮片单用或合用米索前列醇片,观察其终止早孕的临床疗效.结果:115例1次单用米非司酮600mg po组,52例停经天数≤35d者,完全流产率为88.0%;110例合用米索前列醇片600μg po,20例停经天数≤34d者,完全流产率为94.1%,可见合并用药明显提高了抗旱孕的效果(P<0.05).另外,150例又分为3个小组po不同剂量的米非司酮,并合用米索前列醇600μg,各组间完全流产率无显著差异.

【Abstract】 375 early pregnancy cases accepted mifepristone tablet and/or misoprostol tablet in groups at different methods and doses. In 115 cases,in which 52 cases amenorrhea ≤34d,accepted single 600mg mifepristone (group Ⅰ) and 110 cases,in which 20 cases amenorrhea ≤34d, accepted mifepristone 600mg and misoprostol 600mg (group Ⅱ). The complete abortion ratio in groups Ⅰ and Ⅱ was 88.0% and 94.1% respectively (P<0. 05). The another 150 cases accepted different doses of mefepristone and misoprostol 600μg in three groups and there was no significant difference in the complete abortion ratio.

  • 【文献出处】 中国临床药学杂志 ,Chinese Journal of Clinical Pharmacy , 编辑部邮箱 ,1997年01期
  • 【分类号】R169.42
  • 【被引频次】2
  • 【下载频次】16
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