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P53基因在不同类型胃癌细胞内表达的研究
Study of P53 gene expression in different types of stomach carcinoma
【摘要】 目的:探讨不同类型胃癌P53基因表达情况,协助进一步判断肿瘤的恶性程度。方法:用免疫组化ABC法,对不同类型胃癌进行对比检查。结果:胃肝样腺癌P53基因表达明显高于其它类型胃癌。结论:检查胃癌,尤其是胃肝样腺癌P53基因表达,给临床的治疗及判断病人预后提供了重要指标。
【Abstract】 Purpose: To study the P53 gene expressin in different tyes of stomach cancer cells and evaluate the malignant de-gree of the turmor. Methods: Immunohistochemical staining was performed in various types of stomach cancer by a standard a-vidin-biotin-peroxidase(ABC) technique. Results: The expression of P53 gene in hepatoid adenocarcinoma of stomach was higher than other types of gastric carcinoma. Conclusion: Examining P53 gene expression in stomach adenocarcinoma especidlly in the hepatoid adenocacinoma possessed an important significance in evaluating therapeutic effect and its prognosis.
- 【文献出处】 临床肿瘤学杂志 ,Chinese Clinical Oncology , 编辑部邮箱 ,1997年04期
- 【分类号】R735.2
- 【下载频次】44