【摘要】 目的：观察米索前列醇诱导分娩效果。方法：抽取足月妊娠、单胎头位、无高危因素的健康孕妇528例，随机分为对照组（260例）和观察组（268例）。对照组用催产素诱导分娩，观察组用米索前列醇。结果：24小时内观察组促宫颈成熟和引产成功率分别为71．6％和92．5％，高于对照组的50％和78．5％，两项P值均P＜0．05，观察组平均引产时间（10．38小时）短于对照组（13．5小时），有显著差异（P＜0．05）。两组难产率和新生儿出生情况无差异（P＞0．05）。观察组有腹泻、头痛、皮肤搔痒等副反应。结论：米索前列醇用于计划分娩安全有效，但要注意防治宫缩过强、腹泻、头痛等副反应。更多还原

【Abstract】 This paper is aimmed of the observation on the effectiveness of childbith induced by misoprotol. Medthodically, extracted were 528 cases of healthy pregnant women with term pregnancy,monocyesis and with no high-risk factors and randomly grouped were the control group (260 cases )and observation group (268 cases ). In the control group, oxytocin was used to induce childbirth while in obsevation group,misoprotol was used to do that. The results showed that within 24 hours in the observation group, the maturity rate of cervix induced by misoprotol and the successful induced labor rate were 71. 6%and 92. 5% respectively.which were higher than those in the control group (5O% and 78. 5 % respectively .with P<0.05 in the two values ). The average time of inducedlabor in the observation group (10. 38 hours was shorter than that of the cotrol group (13. 5 hours )and there were significant differences (P<0.05 ). In both groups,there were no significant differences in both dystocia and birth condition of the new- born (P>0.05 ).In the observation group there were some side reactions, such as diarrhea,headache and cutaneous pruritus. It’s concluded that micoprotal can be safely used in childbirth control ,but such side reactions as metrypercinesia,diarrhea and headache .eh,should be taken into account and be prevented.更多还原