The bone holes of 3mm in diameter were created on the femur of 6 New Zealand white rahbits and l2 tita-nium cylinder implants of l1mm in length and l. 5mm in diameter inserted in the holes. Afer the placement ofeach implan, space was formed between the implants and bone. Titanium membrane was fixed on the implantand under the periosteum on one femur of animal and without titanium membrane on the other femur as con-trol. The response of muscle to titaniurn membrane was also studied. Results showed that the ...