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实验性糖尿病大鼠的血浆ATⅡ与C肽变化及糖心宁对其影响的实验研究

The Changes of the Levels of Plasma AT Ⅱ and C Peptide in the Rat with Experimental Diabetes and the Influence of Tangxinning over Them

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【作者】 李德伟; 任恩发; 孙红梅; 白丽敏; 吴海霞; 许红; 魏执真; 易京红; 周燕青;

【Author】 Li Dewei, Ren Enfa , Sun Hongmei , et al.(Beijing University of Traditional Chinese Medicine, Beijing 100029)

【机构】 北京中医药大学!北京100029; 北京中医医院!北京100009;

【摘要】 观察了实验性糖尿病大鼠血浆血管紧张素Ⅱ (ATⅡ )、C肽的变化及中药糖心宁对它们的作用。结果表明 ,ATⅡ的含量对照组高于正常组 (P <0 0 1 ) ,治疗组低于对照组 (P <0 0 1 )。C肽的含量对照组低于正常组 (P <0 0 1 ) ,治疗组高于对照组(P <0 0 1 )。ATⅡ的升高可以对心脏产生有害的作用。糖心宁可以提高C肽的含量 ,改善β细胞的功能。糖心宁可能通过多途径作用降低ATⅡ的含量 ,治疗糖尿病心血管并发症

【Abstract】 Changes of plasma AT Ⅱ and C piptide in the rat with experimental diabetes and the effects of TCM preparation Tangxinning over them were observed. The results showed that the AT Ⅱ level of the control group was higher than the normal group ( P <0.01),and that of the treating group was lower than the control group ( P <0.01). The C piptide level of the control group was lower than the normal group ( P <0.01), and that of the treating group was higher than the control group ( P <0.01)

【关键词】 血管紧张素Ⅱ; C肽; 糖心宁; 大鼠;
【Key words】 AT Ⅱ; C Piptide; Tangxinning;
  • 【文献出处】 北京中医药大学学报 ,JOURNAL OF BEIJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE , 编辑部邮箱 ,1997年06期
  • 【分类号】R285.5
  • 【被引频次】1
  • 【下载频次】63
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