【摘要】 为了解两种国产埋植剂对阴道出血模式的影响,并与Norplant进行比较,对自1993年11月1日～1994年5月31日随机接受的857例埋植剂使用者记录的月经卡(其中国产Ⅰ型288份,国产Ⅱ型292份,Norplant277份),采用WHO推荐的参考时段法进行统计分析。结果:各项统计指标三组间差异均无显著意义;总出血天数和滴血天数各参考时段均有减少,自第3参考时段起差异有显著意义;各种出血类型的发生率三组间无差异,有基本正常出血类型的人数自第2参考时段明显增加,为30％～35％;出血不规则的发生率自第2参考时段明显减少,为34％～41％,但仍为各种异常出血的首位;再次使用埋植剂者的总出血天数和出血天数均少于首次使用者,差异有显著意义。初步认为两种国产埋植剂在使用后第1年中对阴道出血模式的影响与Norplant相似,阴道总出血天数随滴血天数的减少而缩短;与使用初期相比,使用三种埋植剂后三个月,有基本正常出血类型的人数明显增加,出血不规则的发生率明显减少,出血不规则是埋植剂使用后月经紊乱的主要表现;再次使用者的出血情况好于初次使用者。更多还原

【Abstract】 Objective:To understand the changes of menstrual bleeding patterns of women using two types of subder-nal sino - implant and compare to that of Norplant. Method: A total of 857 menstrual diaries, provided by three subcentres, were analyzed. They included 288 diaries for sino- implant type 1,292 for type II and 277 for Norplant. The analysis of bleeding patterns was carried out using the reference period approach and followed the guidelings published by WHO. Result:Each index of bleeding patterns was very similar between three groups. The number of bleeding/spotting days and the number of spotting days began to decrease from the second 90 - day period. The number of bleeding days was not much changed per 90 - day period among three groups. The proportions of women experiencing clinically important bleeding patterns were no significant difference instatistics among three groups. The percentage of users experiencing " acceptable" bleeding pattern was increased obviously in the second 90 - day period, from 15% ~ 16% to 28% ~ 33% . The percentage of irregular bleeding, the main bleeding disturbance, was decreased from 51 % - 60% to 34% - 35% in the second 90 - day period. Women using this contraceptive again had shorter bleeding and spotting days than ones using this method first in the firstand second 90 - day period. Conclusion: The influence on mentrual bleeding patterns of subdermal sino - implant type I and type II was similar to that of Norplant in the first year of usine.更多还原