【摘要】 观察了１２名被试者在下体负压作用下脑氧饱和度（ＳｒＯ２）的变化，并作了分析。结果表明：（１）下体负压作用下，ＳｒＯ２呈现显著下降的趋势；（２）在负压终止的时刻，不同状态组之间ＳｒＯ２的变化量差别显著；（３）下体负压作用下ＳａＯ２保持不变，ＳｒＯ２的改变与眶上动脉血流改变的百分数显著相关（ｒ＝０．５９～０．８６，Ｐ＜０．０５或０．０１）。以上结果提示下体负压作用下ＳｒＯ２的改变与脑血流的下降有关，而且用ＳｒＯ２探测晕厥前状态及晕厥是可能的。作者据此推测ＳｒＯ２的监测能够在Ｇ－ＬＯＣ的研究中得到应用。更多还原

【Abstract】 The purpose of this study was to observe and analyse the changes of regional cerebral oxygen saturation (SrO 2) under lower body negative pressure (LBNP). 12 healthy young subjects were tested in an LBNP chamber in sitting position.Incremental negative pressure was used and end points of test were onset of presyncopal symptoms or completion of the 15min test. The results were: (1) SrO 2 showed a significant decrease under LBNP; (2) The magnitude of decrease of SrO 2 showed significant differences among subjects with different reactions at the termination of LBNP; (3) Under LBNP the arterial oxygen saturation (SaO 2) kept constant. The changes of SrO 2 correlated strongly with the percentage changes of superaorbitalis arterial blood flow (r=0.59～0.86, P<0.05 or 0.01). It was suggested that the changes of SrO 2 were related to the decrease of cerebral blood flow under LBNP. It was possible to use SrO 2 to detect presyncopal and syncopal symptoms.So the monitoring of SrO 2 could be used in studies of G-LOC.更多还原