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高生物诱导活性复合人工骨整复骨缺损的超微结构研究

Ultramicrostructure Study of Artificial Bone Composite with\;High Biological Induction in Repairing Bone Defect

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【作者】 费伟; 王大章; 刘松筠;

【Author】 Fei Wei, Wang Dazhang, Liu Songjun\;Department of Oral and Maxillofacial Surgery, West China University of Medical Sciences\;

【机构】 华西医科大学口腔医学院口腔颌面外科学教研室;

【摘要】 采用扫描电镜、X线能谱分析及钙、磷元素微区含量测定等手段 ,对 HA- b BMP- Co和 HA- Co两种不同复合人工骨材料整复节段性骨缺损的机理进行了初步探讨。结果表明 :HA- b BMP- Co复合人工骨具有骨诱导和骨引导的双重作用。除术后 2周磷元素含量无显著性差异外 ,其后同一观察期内 ,HA- b BMP- Co组受植区钙、磷元素含量明显高于 HA- Co组 ,两组间差异有显著性 (P<0 .0 5 )

【Abstract】 The scanning electric microscopy (SEM). X ray energy graph and Ca, P contents analysis were adopted in studying the mechanism and superiority of two different composite artificial bones (HA bBMP Co and HA Co) to repair segmental bone defect in rabbits. The results indicated that HA bBMP Co had a double effects of bone induction and bone conduction. No difference of P content in two weeks after reconstructive surgery was found, but in other periods, there was an obvious difference in Ca and P content between HA bBMP Co group and HA Co group (P<0.05).\;

【基金】 四川省重点科学技术研究项目资助
  • 【文献出处】 华西口腔医学杂志 ,WEST CHINA JOURNAL FOF STOMATOLOGY , 编辑部邮箱 ,1997年01期
  • 【分类号】R783.1
  • 【被引频次】3
  • 【下载频次】35
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