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三种肿瘤标志物对常见肿瘤诊断和预后的应用

Apply the Three Tumor Markers to Diagnosis and Evalute the Curative Effect of Common Carcinoma

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【作者】 黄大鹏; 崔景彬; 赵卫星; 方志慧; 袁麦顺; 姚俊丽;

【Author】 Huang Da-peng Cui Jing-bin Zhou Wei-Sing (Department of Biochemistry,Henan Medical University,Zhengzhou 450052)

【机构】 河南医科大学生物化学教研室; 内黄县人民医院; 鄢陵县计划生育指导站 郑州450052; 郑州450052;

【摘要】 目的:观察血清癌胚抗原(CEA)、血清铁蛋白(SF)和乳酸脱氢酶(LDH)联检对恶性瘤诊断和预后的作用。方法:106例恶性肿瘤患者血清 CEA、SF 用酶联免疫吸附法(ELISA)检测,血清 LDH 同工酶用聚丙烯酰胺凝胶电泳法分析。结果:食管癌、肺癌和乳腺癌的阳性率分别达82%,91%和93%。结论:此三种指标联检可明显提高癌肿的诊断率和评价疗效。

【Abstract】 Objective:The aim of these assay was to observe the effect of carcino-embrynic antigen (CEA),serum ferritin(SF)and lactic dehydrogenase(LDH)on the diagnosis and prognosis of carcino- ma.Methods:The serum levels of CEA and SF were assayed with enzyme linked immunosorbent assay (ELISA),and the isoenzyme pattern of LDH in the serum was studied with polyacrylamide gel elec- trephoresis in 163 patients with carcinoma.Results:The positive rates were 82%,91% and 93% respec- tively in esophagus carcinoma lung cancer and breast cancer.Conclusion:The results demostrate that posi- tive rates of carcinoma were greatly increased when the three targets were assayed at the same time and the markers are valuable in comment response to the therapy.

【基金】 河南省医学科学院科研基金
  • 【文献出处】 河南医学研究 ,Henan Medical Research , 编辑部邮箱 ,1997年01期
  • 【分类号】R730.4
  • 【被引频次】2
  • 【下载频次】52
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