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不同IBD疫苗对SPF鸡的免疫抑制作用
THE IMMUNOSUPPRESSION OF INFECTIOUS BURSAL DISEASE (IBD) VACCINES IN SPECIFIC PATHOGENFREE (SPF) CHICKENS
【摘要】 用A、B、C、D4种IBD毒性型疫苗对6日龄SPF鸡进行免疫接种,根据免疫5d后法氏囊的病理变化、囊/体比、囊指数以及免疫12d后对ND疫苗的免疫应答情况等,综合评定这4种疫苗的免疫抑制作用。结果发现,雏鸡早期免疫IBD毒性型疫苗对法氏囊有明显的损害,其中对囊损伤最轻的是A苗,最严重的是B苗。这4种IBD疫苗均对新城疫疫苗免疫产生免疫抑制作用,其中A苗引起的最轻、最短暂,D苗次之,最严重的是B苗。
【Abstract】 おour kinds of commercial hot IBD vaccines, designated as A,B,C,D were inoculated into 6-day-old SPF chickens. The immunosuppressive effects caused by the IBD vaccines was evaluated according to the bursal histopathological lesions, bursa:body weight index 5 days postinoculation, and immune response to Newcastle Disease(ND) vaccine 12 days after vaccination with the above IBD. It was found that young chickens vaccinated early with the IBD live vaccines exihited marked bursal lesions. The histopathological lesion caused by Vaccine A was the slightest. The lesion caused by vaccine B was most severe. Furthermore, it was demonstrated that admininstration of the four IBD vaccines caused immunosuppression to ND vaccine in SPF chickens. The immunosuppressive effect of four vaccines increased in order by B,C,D,A.
- 【文献出处】 华南农业大学学报 ,JOURNAL OF SOUTH CHINA AGRICULTURAL UNIVERSITY , 编辑部邮箱 ,1997年S1期
- 【分类号】S858.31
- 【被引频次】8
- 【下载频次】65