【摘要】 自1990年10月至1995年3月，作者采用顺铂胸膜腔内化疗，米托蒽醌及环磷酰胺静脉化疗共治疗乳腺癌胸膜转移17例，总有效率为94．1％（16／17），中位生存期17．3个月。胃肠道反应的发生率为76．5％，白细胞减少（Ⅱ、Ⅲ级）占88．2％、所有毒性均可耐受。更多还原

【Abstract】 From October 1990 to March 1995, seventeen patients with pleura metastasis of breast cancer weretreated with cisplatin mitoxantrone and cyciophosthamide. Cispiatin was given intrapleurally and mitoxantrone and cyciophosthamide were given intravenously. The ovelall effective rate was 94. 1% (16/17),and the median survial time was 17. 3 months. Vomiting was seen in 76. 5% and leukopenia (WHO gradeⅡ, Ⅲ ) in 88. 2%. These results indicate that the regimen may be one of the best chemotherapy regimensfor the betment of pleura metastasis of breast cancer.更多还原