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中药R防治食管癌前病变的形态测量学评估

Evaluation of the Effect of Prevention by TCDR on Precursor Lesions of the Esophagus

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【作者】 孙豫赵立群李珊珊

【Author】 Sun Yu; Zhao liqun; Li Shanshan,et al(Department of Oncology and Pathology Henan Institute of Medical Sciences)

【机构】 河南省医学科学研究所!河南省医科所肿瘤病理室450052

【摘要】 应用形态测量的方法,对中药R用于食管癌前病变干预治疗结果进行了评价。并与组织学结果进行了比较。结果显示:基底细胞层厚度在治疗前后统计学显示差异有显著性(P<0.001)。而乳头高度,乳头相对高度和上皮厚度在治疗前后则无统计学意义。组织学结果经配对t检验显示两组间在治疗前后无统计学意义。结果显示:形态测量学可更客观反映组织的病理改变。中药R对改善食管癌前病变中的基底细胞增生可能有一定效果。

【Abstract】 on the treatment of precursor lesions of the be and was Compared with histologic features. It was found tha basal cell zone was greatly improved after treatment (P < 0.001). However,the heigh and the relative height of bona Propia papillae and epithelial thickness were not statistically significant before and after treatment The matehed - pair test indicatal tha no statistic ffere was bon the R group and the placebe group by histologic examination . It is suggested that the morphometric measurement is on objective than histologic findings Thiss study showed tha traditional Chinese herb R can reduce the basal cell hyperplasia.

【关键词】 形态测量中药食管癌前病变
【Key words】 morphometryChinese herbesophagusprecursor lesions
  • 【文献出处】 河南肿瘤学杂志 ,HENAN JOURNAL OF ONCOLOGY , 编辑部邮箱 ,1997年03期
  • 【分类号】R735.1
  • 【被引频次】4
  • 【下载频次】33
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