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食管癌术后预后的逐步回归分析
Stepwisely Regressive Analysis of the Prognostic Factors of the Esophageal Carcinoma after Radical Resection
【摘要】 通过对143例根治术后的食管癌患者的预后进行统计学分析,评价各预后因素的实际价值。我们选择1984年4月到1989年4月间143例根治术后的食管癌进行随访,对其各种预后因素先用单因素分析,筛选出有意义的因素,再进行逐步回归分析(a=0.05),评价各因素对食管癌根治术后预后的影响。单因素分析表示:PT,RN,组织分化,肉眼分型,手术径路,肿瘤长度和多源发对食管癌根治术后的预后产生影响(P<o.01~0.05)。逐步回归分析提示:pT,PN和手术径路是影响食管癌术后预后的重要因素。食管癌浸润深度和淋巴结的转移状况是影响食管癌预后的重要因素,要提高其术后的5年生存率必须加强两个以上区域淋巴结的清扫。
【Abstract】 Our purpose is to assess the predictive value of prognstic factors by a statstical edysis of thePIDgnostic factors in 143 Paients after radical resection of the esophageal careinorna. We selected andfollowed-up 143 patients with esophageal cancer aller ndical resection from April 1984 to April 1989.Follow-up survey was cAned out every year. Univallate analysis was performed among eleven factors andstepwisely regnssive analysis (a = O.05) was then used for multivariate analysis to assess the Pndctivevalue of prognostic factors.The whvariate analysis showed that the following factors had sigidricant deton PIDgnosis, such as pp, PN, histompc grading, macrosopic aPpearece, operative aPproach, tuinr lengthand multifocality of cancer (P < 0. 0l ~ 0. 05 ). Multivallate analysis showed that rr, PN and operativeaPProach were impt prognoShc fact0rs. The present study shoiws that nedal statUs and depth of wallpenermtion are important prognoShc faCtors for careinoma of the esophagUs after ndical resection. ThelymPhadenect0my including tW0 or be fields along with esophagectomy is nicesmp to improve 5-yearsurvial rate.
- 【文献出处】 河南肿瘤学杂志 ,HENAN JOURNAL OF ONCOLOGY , 编辑部邮箱 ,1997年02期
- 【分类号】R735.1
- 【被引频次】3
- 【下载频次】47