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宫颈癌患者宫颈粘液CEA测定的临床意义

Clinical Significance of Cervical Mucus CEA Assay in Patients with Carcinoma of the Cervix

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【作者】 苗华芹; 东野美樽; 张华; 张鹏; 周登峰; 方永存;

【Author】 Miao Huaqin; Dongye Meizun; Zhang Hua; et al(Shandong Tumor Prevention and Treatment Institute ,Jinan 250117)

【机构】 山东省肿瘤防治研究院;

【摘要】 应用放射免疫技术对50例宫颈癌患者及24例非恶性肿瘤患者的宫颈粘液及外周血CEA的含量进行了测定,结果:宫颈癌患者宫颈粘液CEA测定值及阳性率明显高于对照组(P<0.05,P<0.01)。良、恶性病变的宫颈粘液CEA均明显高于外周血中CEA含量(P<0.01,P<0.02)。而宫颈癌患者血CEA测定值及阳性率与对照组比较均无差异(P>0.05)。宫颈癌患者治疗前、后宫颈粘液CEA测定值差异有显著性(P<0.01)。作者认为:宫颈粘液CEA的测定对宫颈癌的诊断及疗效评价较血CEA的测定更有意义。

【Abstract】 The CEA coto of cervical mucus patients and periphend serum was detendned in 50 cerricalareinoma patients and 24 nonmalignant tumor patients by a radioimmunoassay technique, The CEA levelsand positive rate of cervical mucus in cewical carcinoma group were significantly higher than that incontrol group (P <0.05 ana P < 0.01 respectively) .The levels of cervical mucus CEA in benigh andmalignant Patients were significantly higher than those of peripheral serum CEA(P < 0.01 and P <0.02,respectively). There was no significant no in serum CEA leve and positive rate betweencervical cance group and control group(P > 0.05). There was a significant dence about cervicalmucus CEA in cervical carcinoma Patients before and after treatment (P <0. 01 ). The writers of thisarticle think tha the CEA level of cervical mucus is a more useful index than that of the serum indiagnozing and evalusting the curative effect of cervical cancer.

【关键词】 宫颈粘液; CEA; 宫颈癌;
【Key words】 cewical mucus; CEA; cervical cancer;
  • 【文献出处】 河南肿瘤学杂志 ,HENAN JOURNAL OF ONCOLOGY , 编辑部邮箱 ,1997年01期
  • 【分类号】R737.33
  • 【下载频次】29
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