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胃癌患者红细胞C3b受体与自然杀伤细胞活性的相关性研究

RELATIONSHIP BETWEEN RBC-C3b RECEPTOR AND NATURAL KILLING CELL ACTIVITY IN PATIENT WITH GASTRIC CANCER

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【作者】 任金荣艾军何兰欣张雪莉郑宝军李勇

【Author】 Ren Jinrong Ai Jun He Lanxin Zhang Xueli Tumor Institute of Hebei Province Zheng Baojun Li Yong Department of Surgery,Fourth Clinical Medical College

【机构】 河北省肿瘤研究所

【摘要】 为研究胃癌患者的红细胞C3b受体(RBCC3bR)与自然杀伤(NK)细胞活性之间的关系,利用酵母菌花环试验及MTT比色法对30例胃癌患者及38例健康对照者的RBCC3b受体及NK细胞活性进行了测定。结果表明胃癌患者的这两项免疫指标均比正常对照组显著低下(P<0.01)。经统计学相关性分析显示,这两项免疫指标间呈明显的正相关(r=0.607,P<0.001)。

【Abstract】 In order to clarify the relationship between RBC-C3b receptors and natural killing(NK) cell activity,30 cases of gastric cancer and 38 cases of normal subjects were measured by C3b rosete test(rosete formation with Zymosan particles treated by guinea pig complement) and MTT-assay.The results showed that both RBC-C3b receptor and NK cell activity in patients with gastric cancer were lower than that of control group(P<0.01).A significant correlation exists between the RBC-C3b receptors and NK cell activity in patients with gastric cancer(r=0.067,P<0.01).

  • 【文献出处】 河北医科大学学报 ,JOURNAL OF HEBEI MEDICAL UNIVERSITY , 编辑部邮箱 ,1997年06期
  • 【分类号】R735.2
  • 【下载频次】12
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