【摘要】 为探讨老年高血压患者的血浆肾素活性（PRA）、血管紧张素Ⅱ（AngⅡ）水平与动态血压各参数值的关系，对57例老年高血压患者及26例健康老人在平衡饮食后行PRA、Ang－Ⅱ水平检查及24小时动态血压监测。结果显示：高血压组动态血压各参数值均显著高于对照组；与肾素正常者相比，高血压组中肾素增高者（PRA＞88ng／L／h）夜间平均收缩压、夜间平均舒张压及血压负荷值显著增高（P＜0．05），其夜间血压下降率＜10％。提示高肾素型老年高血压患者的24小时血压节律消失，血压负荷值尤其是夜间血压负荷明显升高，易引起各靶器官的功能损害应引起重视。更多还原

【Abstract】 We reserched the relationship of plasma renin activity (PRA), angiotensin Ⅱ(Ang -Ⅱ) and24 hour ambulertory blood pressure mornitoring (ABMP) in elderly essential hypertensive patients.Motheds After balance diet for 7 days, we analysed the level of PRA, Ang-Ⅱand ABPM in57 elderly easential hypertensive pantients and 26 cases normoltensive healthy elderly people.Results The ABPM level in hypertensive group was much higher than that in the normotensivegroup (P < 0.01). The hypertensive group was divided into two groups: PRA≥800ng/L/h wasGroup A, PRA <800ng/L/h was Group B. Night systtolic blood pressare, night diastoic bloodpressure and 24 hour BP load in Group A were signifeantly higher than those of Group B (P < 0.01). The night blood pressure descent rate of Group A was < 10%.Conclusion The high PRA type elderly hypertensive patients had the higher risk of targetorgan damage.更多还原