【摘要】 用酶组织化学方法探讨经支气管纤维镜（简称纤支镜）活检组织，对肺癌的早期诊断。包括一氧化氮合酶（ＮＯＳ）、细胞色素氧化酶（ＣＣＯ）、乳酸脱氢酶（ＬＤＨ）、琥珀酸脱氢酶（ＳＤＨ）、酸性磷酸酶（ＡＣＰ）等。酶组织化学反应结果显示为肺癌组病人ＮＯＳ、ＬＤＨ、ＣＣＯ、ＡＣＰ的活性显著增高，分别为强阳性（），少数呈最强阳性（）；而ＳＯＨ活性为弱阳性（＋），较正常人组显著下降。可疑组病人ＳＤＨ活性增高呈强阳性（）或最强阳性（），但ＮＯＳ、ＬＤＨ、ＡＣＰ的活性较肺癌组下降，分别为弱阳性（＋）或中等阳性（）。上述结果提示：ＮＯＳ等活性的变化，可作为提高肺癌早期诊断的重要指标之一。更多还原

【Abstract】 50 patients were divided into 3 groups: group A 10 for normal control, group B 20 cancer of Lung, group C 20 suspected cases. Fibrobiomicroscope biopsy of Lung and bronchas was performed respectively; then the changes of the enzyme histochemistry of the bronchas and Lung were observed. The results showed that in group B the activities of NOS. LOH. CCO. ACP. reaction were significantly high (strong positive in the cytoplasm of brchas muscosa), while the activit of SDH was decreased, lower than in group A or group C. It is suggeted that the changes of enzymehistochemistry reaction of NOS and other enzymes may contribute to making early diagnoses for lung cancer.更多还原