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一种新型甘油三酯吸附剂的制备及其对血清中甘油三酯的吸附性能研究

The Preparation of a Novel Adsorbent for Triglyceride and Its Adsorption Properties for Triglyceride in Serum

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【作者】 余艺华孙君坦何炳林顾汉卿

【Author】 YU Yi-Hua, SUN Jun-Tan, HE Bing-Lin(Institute of Polymer Chemistry, The State Key Laboratory of Functional Polymer Materials forAdsorption and Separation, Nankai University, Tianjin, 300071 )GU Han-Qing(Tianjin institute of Urological Surgery, Tianjin, 30

【机构】 南开大学高分子化学研究所!天津300071天津泌尿外科研究所!天津300211

【摘要】 合成了一种新型的甘油三酯吸附剂-磺化羟乙基化交联壳聚糖,用其对血浆中甘油三酯进行吸附.实验结果表明,该吸附剂最高可使血清中的甘油三酯降低76.9%(每克树脂吸附量为6.25mg),而对血清中总蛋白(TP)的吸附较少.

【Abstract】 Sulfonated hydroxyethylated crosslinked chitosan beads, which can selectively adsorb triglyceride, were prepared by the reaction of hydroxyethylated crosslinked chitosan and ClSO3H, using DMF as solvent. Adsorption experiments were performed by adding thebeads to the serum. The results showed that this type of adsorbent could cut down the concentration of triglyceride in plasma by 76. 9% at most, while the concentration of total protein(TP) decreased only by 2. 6% at least, so this novel adsorbent can be expected to be used for curing hypertriglyceridemia in the future.

【基金】 国家自然科学基金
  • 【文献出处】 高等学校化学学报 ,CHEMICAL RESEARCH IN CHINESE UNIVERSITIES , 编辑部邮箱 ,1997年10期
  • 【分类号】O647
  • 【被引频次】14
  • 【下载频次】120
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