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金丝桃蒽酮与竹红菌甲素光敏作用及暗反应特征的比较
COMPARISON BETWEEN CHARACTERS OF PHOTO SENSITIZATION AND DARK REACTION OF HYPERICIN AND HYPOCRELLIN A
【摘要】 在DMSO均相体系中研究了金丝桃蒽酮(HYP)光敏作用及暗反应的特征,测得HYP产生1O2与产生·OH的速率常数之比为0.057,产生1O2与产生HYP·-的速率常数之比为1.25,发现HYP在以半胱氨酸为还原剂的条件下,通过热化学作用即可产生O2·-,但O2·-产额低于竹红菌甲素(HA)。在TX-100胶束非均相体系中,比较了HYP与HA光敏产生1O2、·OH的产额,发现它们1O2产额相近,而HYP的·OH产额高于HA。
【Abstract】 Characteristics of photosensitization and dark reaction of hypericin(HYP) are studied in DMSO homogeneous system Rate constant ratio of HYP of generating O 2 1 to O ·- 2 isdetermined as 0 057 and rate constant ratio of generating O 2 1 to anionradical of HYP(HYP ·- ) is determined as 1 25 It is also found that in existence of cysteine, HYP produce O ·- 2 through thermochemica reaction, but the amount of O ·- 2 is lower than that produced by HA In TX 100 micellarheterogeneous system, amounts of produced 1O 2 and ·OH through photosensitization of HYP and HA are compared and it is found that the amount of generated 1O 2 is similar to each other, but amount of produced ·OH of HYP is higher than that of HA
【Key words】 Hypericin; Hypopcrellin A; Active oxygen free radical; Spin trapping; ESR; Photosensitization; Dark reaction;
- 【文献出处】 辐射研究与辐射工艺学报 ,JOURNAL OF RADIATION RESEARCH AND RADIATION PROCESSING , 编辑部邮箱 ,1997年03期
- 【分类号】Q939
- 【被引频次】4
- 【下载频次】46