【摘要】 本实验采用ＧＣ／ＭＳ分离、鉴定新会柑皮抗小鼠髓性单核细胞性白血病提取物中的５种成分，即化合物I为４’，５，６，７，８－五甲氧基黄酮，化合物Ⅱ为４’，５，７，８－四甲氧基黄酮，化合物Ⅲ为５－羟基，３’，４’，６，７，８－五甲氧基黄酮，化合物Ⅳ为３’，４’，５，６，７，８－六甲氧基黄酮，化合物Ｖ为３’，４’，５，７，８－五甲氧基黄酮。这与ＰＭＲ谱和ＵＶ谱分析相符。其中化合物Ⅰ、Ⅲ、Ⅳ抑制白细胞生长 ５０％所需的浓度分别为 ２．９，２．５，２．８ ｍｇ／Ｌ。更多还原

【Abstract】 In this report,GC/MS was used for separating and identifying five components of anti-mouse myeloid leukemic cells extracted from Xinhui citrus peel, and compared with NMR and UV data. The compound I is 4’,5, 6,7,8-pentamethoxyflavone, compound Ⅱis 4’, 5, 7, 8-butamethoxyflavone, compound Ⅲ is 5-hydroxy-3’, 4’, 6, 7, 8-pen- tamethoxyflavone, compound Ⅳ is 3’, 4’, 5, 6, 7, 8-hexamethoxyflavone, compound V is 3’, 4’, 5, 7, 8-pentamethoxyflavone. Among these compounds, the concentrations of com- pound Ⅰ、Ⅲ、Ⅳ needed for inhibiting 50% growth rate of leukemic cells are 2. 9,2. 5, 2. 8 mg/L respectively.更多还原