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腐植酸拮抗病毒感染的实验研究
EXPERIMENTAL STUDY ON ANTIVIRAL MECHANISM OF HUMIC ACID
【摘要】 研究显示生物工程工艺制备生产的腐植酸对疫苗病毒的繁殖有显著的抑制作用(P<0.01),而对正常传代细胞无毒性表现(P>0.05)。腐植酸能诱导小鼠体内产生干扰素。同时也能在体外诱导小鼠巨噬细胞产生干扰素,并能增强小鼠自然杀伤细胞活性(P<0.01)。
【Abstract】 The initial results indicated that humic acid produced by engineering could significantly inhibit the proliferation of vaccinia virus(P<0.01),while it had no toxicity on the normal cell lines(P>0.05).We also found that humic acid could induce not only mice in vivo but also macrophage in vitro to produce interferon,and could increase natural killer cell(NK cell)activity in mice.From the results the humic acid can be treated as a new antiviral drug that has a potential prospect.
- 【文献出处】 承德医学院学报 ,Journal of Chengdu Medical College , 编辑部邮箱 ,1997年02期
- 【分类号】R965
- 【被引频次】2
- 【下载频次】31