节点文献
化学脱色法制备白癜风动物模型
MAKE A ANIMAL PATHOLGICAL OF VITILLIGO IN CHEMICAL DECOLOR METHOD
【摘要】 用5%过氧化氢外涂豚鼠脱毛区20、30和40d后,使豚鼠皮肤色素减少,呈苍白或白斑状,MAO活性增加,ChE活性下降,Ig含量增高,有模拟白癜风的作用。
【Abstract】 A continuous adminstration of 5% H2O2 to guinea pigs on the dehair for 20,30and 40 days respectively could result in a noticeably reduce of skin melanin,and there were pale or wihte area on the dehair skin,an increase of serum monoamine oxidase activity and serum cholinesterase activity,and increase of immunoglobutins.This suggests that the use of 5% H2O2 has minic effect of vitilligo on the animals.
【关键词】 白癜风;
化学脱色法;
动物模型;
黑色素;
【Key words】 Vitilligo; Chemical decolor method; Animal pathological pattern; Melanin;
【Key words】 Vitilligo; Chemical decolor method; Animal pathological pattern; Melanin;
【基金】 安徽省科技基金
- 【文献出处】 安徽中医学院学报 ,JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE , 编辑部邮箱 ,1997年06期
- 【分类号】R758.41
- 【被引频次】60
- 【下载频次】452