【摘要】 本文动态观察４０例脑梗塞（ＣＩ）患者血浆降钙素基因相关肽（ＣＧＲＰ）及血管紧张素Ⅱ（ＡⅡ）的变化。结果发现：ＣＩ病程３天内及１０～１４天，血浆ＣＧＲＰ高于病程２５～２８天者及脑动脉硬化组，ＣＩ整个病程中血浆ＣＧＲＰ均低于正常对照组。血浆ＡⅡ在ＣＩ病程３天内及１０～１４天均高于２５～２８天，脑动脉硬化组及正常对照组，病程２５～２８天者与脑动脉硬化组无显著性差异，但二者均高于正常对照组，脑梗塞伴高血压者，血浆ＡⅡ高于不伴高血压者，而ＣＧＲＰ低于不伴高血压者。提示血中ＣＧＲＰ不足及ＡⅡ增高，是高血压、动脉硬化及脑梗塞发病的重要因素。更多还原

【Abstract】 We have studied the changes of plasma calcitonin gene-related peptide (P-CGRP) and angiotensid Ⅱ (P-AⅡ) levels in 40 patients with cerebral infarction. The results showed that the P-CGRP levels of cerebral infarction patients within the 3 days and 10-14 days after onset were higher than of patinets within 25-28 days and cerebral ath erosclerosis paitents, the P-CGRP levels of cerebral infarction patients in the total process were lowere than that of the normal controls. The P-AⅡ levels of cerebral inforction patients within the 3 days and 10-14 days after onset were higher than that of the cerebral infaretion patinets within 25-28 days, cerebral atherosclerosis patinet and normal controls, the P-AⅡ levels have no difference between the cerebral infarction patients within 25-28 days after onset and cerebral atherosclerosis patients, but both of that were higher than normal controls. The P-AⅡ levels of cerebral infarction patients with hypertension were higher than that with no hypertension, the P-CGRP levels of cerebral infarction patients with hypertension were lower than that with no hypertension, The results suggest that P-CGRP decrsase and P-AⅡ increase are the important reasons of hypertension, cerebral atherosclerosis and cerebral infaction.更多还原