【摘要】 本文研究了卤虫（Ａｒｔｅｍｉａｐａｒｔｈｅｎｏｇｅｎｅｔｉｃａ）对下述３种药物的摄入与排出：磺胺嘧啶（ＳＤ）、土霉素（ＯＴＣ）及无味红霉素（ＥＲＹ－Ｅｓ）。当摄取药物１小时（药物用海水配制成混悬液）时，卤虫（幼体或成体）消化道充满了白色的药物颗粒；经测定此时初孵无节幼体内药物含量为１７μｇ／１０只，成体内为２０３μｇ／只（体长６５ｍｍ）及３６２μｇ／只（体长９２ｍｍ）。药物颗粒大小、摄取时间及卤虫体长对药物摄入量有明显影响。但卤虫对３种药物的摄取量无明显差异。当将载药卤虫放入海水中３小时时，仅有５０％的药物被排出。更多还原

【Abstract】 The ingestion and excretion of the following antibacterial drugs by the brine shrimp (Artemia parthenogenetica) of various growth stages were studied: sulfadiazine (SD), oxytetracycline (OTC) and erythromycin estolate (ERY-Es). After Artemia had ingested drugs in the seawater suspentions for 1 hour, the digestive tracts of both nauplii and adults were filled with drug particles; the content of drugs in newly-hatched nauplii was 1.7μg/10 nauplii and in adults was 20.3μg/individual (6.5mm in length) and 36.2μg/individual (9.2mm in length). The following parameters: particle size, ingestion period and body length of Artemia, have shown to have obvious effects on the process of ingestion or bio-encapsulation. There was not significant difference in the amount of ingestion among various drugs. About 50% of drugs were excreted after the drug-incorporated brine shrimp was removed to seawater for 3 hours.更多还原